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49ers vs Cardinals Prediction and Preview - NFL Week 5, 2024

The San Francisco 49ers will sqaure off with the Arizona Cardinals in NFL Week 5 action at Levi's Stadium on Monday, beginning at 7:05am AEDT.

This article features Stats Insider's best betting tips for the 49ers vs Cardinals game, plus the latest betting odds and touchdown scorer tips.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the outcome of Monday's San Francisco vs Arizona NFL match-up 10,000 times.

Our leading predictive analytics model gives the 49ers a 72% chance of defeating the Cardinals at Levi's Stadium.

49ers vs Cardinals: Odds

The latest Bet365 betting odds in Australia for Monday's NFL game at Levi's Stadium are listed here:

  • Head to Head: 49ers $1.28, Cardinals $3.80
  • Line: 49ers -7 ($1.91), Cardinals +7 ($1.91)
  • Total (Over/Under 49 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the 49ers at $1.28 and the Cardinals at $3.80.

The 49ers are 7-point favourites against the Cardinals, with odds of $1.91 available at Bet365.

For the underdog Cardinals (+7) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 49 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+7) are predicted to cover the line 54% of the time, while the 49-point over/under is expected to stay under 51% of the time.

49ers vs Cardinals: Betting Tips

  • Head to Head: Arizona at $3.80 with Bet365
  • Line: Cardinals +7 at $1.91 with Bet365
  • Total Points: Under 49 at $1.91 with Bet365

 
Stats Insider's 49ers vs Cardinals predictions are based on world-class simulations and gambling expertise to provide you with the best possible advice around the clock.

While the 49ers have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the 1.7% edge identified when comparing our data-driven probabilities to the odds currently available.

Taking advantage of the edges seen here at Stats Insider is crucial to being profitable in the long run.

49ers vs Cardinals: Prediction

Stats Insider's predicted final score for 49ers vs Cardinals at Levi's Stadium in Week 5 is the 49ers winning 27-20.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full coverage of the San Francisco vs Arizona game in Week 5, including data-driven predictions and top betting tips.

For in-depth analysis from US experts,, check out Dimers' detailed 49ers vs Cardinals prediction.

49ers vs Cardinals: TD Scorer Tips

Who will score the first touchdown in 49ers vs Cardinals? The latest data is in.

According to Stats Insider, San Francisco's Jordan Mason is the most likely player to score the first TD in 49ers vs Cardinals.

Mason has a 15.5% chance of scoring the first TD at Levi's Stadium, while the 49ers RB has a 60.8% chance of scoring an anytime touchdown.

Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.

First Touchdown Scorer Tips

49ers First TD Tips

  • Jordan Mason: 15.5% probability
  • Deebo Samuel: 9.6% probability
  • Brandon Aiyuk: 8.4% probability
  • George Kittle: 8.1% probability
  • Jauan Jennings: 7.0% probability

Cardinals First TD Tips

  • James Conner: 9.9% probability
  • Marvin Harrison: 7.3% probability
  • Trey McBride: 6.3% probability
  • Kyler Murray: 5.3% probability
  • Michael Wilson: 4.6% probability

Anytime Touchdown Scorer Tips

49ers Anytime TD Tips

  • Jordan Mason: 60.8% probability
  • Deebo Samuel: 43.4% probability
  • Brandon Aiyuk: 39.6% probability
  • George Kittle: 37.8% probability
  • Jauan Jennings: 32.6% probability

Cardinals Anytime TD Tips

  • James Conner: 45.5% probability
  • Marvin Harrison: 36.0% probability
  • Trey McBride: 29.3% probability
  • Kyler Murray: 26.6% probability
  • Michael Wilson: 23.6% probability

49ers-Cardinals Projected Player Stats

Of the starting quarterbacks, the 49ers' Brock Purdy is projected for 289 passing yards, while the Cardinals' Kyler Murray is expected to throw for 207 yards.

49ers Starting QB

  • Brock Purdy: 289 projected passing yards

Cardinals Starting QB

  • Kyler Murray: 207 projected passing yards

49ers Rushing Yards

  • Jordan Mason: 91 projected yards
  • Brock Purdy: 13 projected yards
  • Deebo Samuel: 12 projected yards

Cardinals Rushing Yards

  • James Conner: 73 projected yards
  • Kyler Murray: 33 projected yards
  • Trey Benson: 14 projected yards

49ers Receiving Yards

  • Brandon Aiyuk: 60 projected yards
  • George Kittle: 53 projected yards
  • Deebo Samuel: 52 projected yards
  • Jauan Jennings: 37 projected yards
  • Jordan Mason: 14 projected yards

Cardinals Receiving Yards

  • Marvin Harrison: 56 projected yards
  • Trey McBride: 55 projected yards
  • Michael Wilson: 41 projected yards
  • Greg Dortch: 34 projected yards
  • Elijah Higgins: 14 projected yards

Remember, our model updates frequently, so keep checking this article for the latest betting analysis before the San Francisco vs Arizona match-up.

As always, see Stats Insider's Best Bets for betting tips on every NFL game, plus predictions for a wide range of other sports.

49ers vs Cardinals: Week 5 Essential Details

The NFL Week 5 game between the 49ers and Cardinals at Levi's Stadium is scheduled to begin at 7:05am AEDT on Monday.

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.

Conclusion

Our San Francisco vs Arizona predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our NFL predictions for betting purposes, it's important that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on NFL

Stats Insider is your go-to source for betting on the NFL in Australia, with the latest NFL betting news, predictions for every NFL game, and Super Bowl odds for the NFL.

Ryan Leaver

Ryan Leaver is a respected journalist and lifelong sports fan who is widely regarded as one of Australia's most trusted sources for accurate and up-to-date information across various sports. He holds a Bachelor's Degree in Journalism (Sport) from La Trobe University, which strengthens his credibility in the field. Ryan, who previously worked at Triple M, where he provided comprehensive coverage of the AFL and cricket, is renowned for his extensive knowledge and ability to deliver the latest insights.

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