Astros vs Padres Prediction and MLB Tips - 21 April 2025
Apr 20, 2025, 1:29AM
The Houston Astros will take on the San Diego Padres in MLB action at Daikin Park on Monday, starting at 9:10am AEST.
The Astros will send Framber Valdez (1-2, 4.91 ERA) to the mound, up against Dylan Cease (1-1, 6.64 ERA) for the Padres.
This article features Stats Insider's best betting tips for the Astros vs Padres game, along with the latest betting odds in Australia.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the result of Monday's Houston vs San Diego MLB game 10,000 times.
Our leading predictive analytics model currently gives the Astros a 55% chance of beating the Padres at Daikin Park.
Astros vs Padres: Odds
The latest betting odds in Australia for Monday's MLB game at Daikin Park are listed here:
- Head to Head: Astros $1.80, Padres $2.05
- Line: Astros -1.5 ($2.75), Padres +1.5 ($1.48)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Astros at $1.80 and the Padres at $2.05.
The Astros are 1.5-run favourites against the Padres, with odds of $2.75 available at TAB.
For the underdog Padres (+1.5) to cover the line, TAB offers odds of $1.48.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Padres (+1.5) are predicted to cover the line 64% of the time, while the 7.5-run over/under is expected to stay under 52% of the time.
Astros vs Padres: Betting Tips
- Head to Head: Houston at $1.80 with TAB
- Line: Astros -1.5 at $2.75 with TAB
- Total Runs: Under 7.5 at $1.91 with TAB
Today's Astros vs Padres betting tips are based on world-class simulations and gambling expertise to help you place better bets with your chosen online bookie.
Even though the Padres are more likely to cover the line, our best bet of Astros -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the top odds available.
Astros vs Padres: Prediction
Stats Insider provides full betting coverage of the Houston vs San Diego game on Monday, including data-driven predictions and live updatestips.
Our model updates regularly, so refresh this article for the latest betting predictions before the Houston vs San Diego game.
As always, see our Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.
Astros vs Padres: Essential Details
The game between the Astros and Padres at Daikin Park is scheduled to commence at 9:10am AEST on Monday.
- Teams: Houston Astros vs San Diego Padres
- Date: Monday 21 April 2025
- Time: 9:10am AEST
- Venue: Daikin Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Houston vs San Diego predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.
