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Bills vs Cardinals Prediction and Preview - NFL Week 1, 2024

The Buffalo Bills will take on the Arizona Cardinals in NFL Week 1 action at Highmark Stadium on Monday, beginning at 3:00am AEST.

This article features Stats Insider's top betting tips for the Bills vs Cardinals game, as well as the latest betting odds and touchdown scorer tips.

Who Will Win?

Based on trusted computer power and data, Stats Insider has simulated the result of Monday's Buffalo vs Arizona NFL game 10,000 times.

Our proven predictive analytics model gives the Bills a 71% chance of beating the Cardinals in Week 1 of the NFL season.

Bills vs Cardinals: Odds

The latest Bet365 betting odds in Australia for Monday's NFL game at Highmark Stadium are listed below:

  • Head to Head: Bills $1.33, Cardinals $3.45
  • Line: Bills -6.5 ($1.91), Cardinals +6.5 ($1.91)
  • Total (Over/Under 45.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Bills at $1.33 and the Cardinals at $3.45.

The Bills are 6.5-point favourites against the Cardinals, with odds of $1.91 available at Bet365.

For the underdog Cardinals (+6.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 45.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Cardinals (+6.5) are predicted to cover the line 57% of the time, while the 45.5-point over/under is expected to go over 51% of the time.

Bills vs Cardinals: Betting Tips

  • Head to Head: Arizona at $3.45 with Bet365
  • Line: Cardinals +6.5 at $1.91 with Bet365
  • Total Points: Over 45.5 at $1.91 with Bet365

 
When you see a 🔥, you know it's one of our best bets for today across all sports.

Today's Bills vs Cardinals predictions are based on detailed modelling and wagering experience to give you the best possible advice around the clock.

While the Bills have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the edge identified when comparing our data-driven probabilities to the odds currently available.

Taking advantage of the edges seen on Stats Insider is one of the keys to achieving long-term success as a bettor.

Bills vs Cardinals: Prediction

Stats Insider's predicted final score for Bills vs Cardinals at Highmark Stadium in Week 1 is the Bills winning 25-19.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full coverage of the Buffalo vs Arizona game in Week 1, including data-driven predictions and free betting tips.

Bills vs Cardinals: TD Scorer Tips

Who will score the first touchdown in Bills vs Cardinals? The latest data is in.

According to Stats Insider, Buffalo's Josh Allen is the most likely player to score the first touchdown in Bills vs Cardinals.

Allen has an 11.6% chance of scoring the first TD at Highmark Stadium, while the Bills QB has a 47.1% chance of reaching the end zone at any point in the game.

Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.

First Touchdown Scorer Tips

Bills First TD Tips

  • Josh Allen: 11.6% probability
  • James Cook: 8.0% probability
  • Dalton Kincaid: 5.9% probability
  • Khalil Shakir: 5.6% probability
  • Keon Coleman: 5.3% probability

Cardinals First TD Tips

  • James Conner: 8.9% probability
  • Marvin Harrison: 6.7% probability
  • Kyler Murray: 5.5% probability
  • Trey McBride: 5.4% probability
  • Michael Wilson: 3.9% probability

Anytime Touchdown Scorer Tips

Bills Anytime TD Tips

  • Josh Allen: 47.1% probability
  • James Cook: 35.0% probability
  • Dalton Kincaid: 27.2% probability
  • Khalil Shakir: 25.4% probability
  • Keon Coleman: 24.8% probability

Cardinals Anytime TD Tips

  • James Conner: 39.7% probability
  • Marvin Harrison: 30.9% probability
  • Kyler Murray: 26.1% probability
  • Trey McBride: 25.2% probability
  • Michael Wilson: 19.5% probability

Bills-Cardinals Projected Player Stats

Of the starting quarterbacks, the Bills' Josh Allen is projected for 245 passing yards. The Cardinals' Kyler Murray is expected to throw for 217 yards.

Bills Starting QB

  • Josh Allen: 245 projected passing yards

Cardinals Starting QB

  • Kyler Murray: 217 projected passing yards

Bills Rushing Yards

  • James Cook: 57 projected yards
  • Josh Allen: 36 projected yards
  • Ray Davis: 23 projected yards

Cardinals Rushing Yards

  • James Conner: 63 projected yards
  • Kyler Murray: 34 projected yards
  • Trey Benson: 22 projected yards

Bills Receiving Yards

  • Khalil Shakir: 52 projected yards
  • Dalton Kincaid: 50 projected yards
  • Keon Coleman: 42 projected yards
  • Curtis Samuel: 34 projected yards
  • James Cook: 23 projected yards

Cardinals Receiving Yards

  • Trey McBride: 59 projected yards
  • Marvin Harrison: 57 projected yards
  • Greg Dortch: 39 projected yards
  • Michael Wilson: 33 projected yards
  • Chris Moore: 15 projected yards

Our model updates regularly, so refresh this article for the latest betting analysis before the Buffalo vs Arizona match-up.

As always, see our Best Bets for betting tips for every NFL game, as well as predictions for a wide range of other sports.

Bills vs Cardinals: Week 1 Essential Details

The NFL Week 1 game between the Bills and Cardinals at Highmark Stadium is scheduled to begin at 3:00am AEST on Monday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Buffalo vs Arizona predictions are based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on NFL

Stats Insider is your go-to source for betting on the NFL in Australia, with the latest NFL betting news, tips for every NFL game, and Super Bowl probabilities for the NFL.

Ryan Leaver

Ryan Leaver is a respected journalist and lifelong sports fan who is widely regarded as one of Australia's most trusted sources for accurate and up-to-date information across various sports. He holds a Bachelor's Degree in Journalism (Sport) from La Trobe University, which strengthens his credibility in the field. Ryan, who previously worked at Triple M, where he provided comprehensive coverage of the AFL and cricket, is renowned for his extensive knowledge and ability to deliver the latest insights.

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