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Cardinals vs Astros Prediction and MLB Tips - 17 April 2025

The St. Louis Cardinals will take on the Houston Astros in MLB action at Busch Stadium on Thursday, commencing at 3:15am AEST.

The Cardinals will have Steven Matz (0-0, 2.31 ERA) start, while the Astros will counter with Ronel Blanco (1-1, 6.94 ERA).

This article features Stats Insider's top betting tips for the Cardinals vs Astros game, along with the latest betting odds in Australia.

Who Will Win?

Based on advanced computer power and data, Stats Insider has simulated the result of Thursday's St. Louis vs Houston MLB game 10,000 times.

Our proven predictive analytics model currently gives the Astros a 52% chance of winning against the Cardinals at Busch Stadium.

Cardinals vs Astros: Odds

The latest betting odds in Australia for Thursday's MLB game at Busch Stadium are shown below:

  • Head to Head: Cardinals $1.95, Astros $1.87
  • Line: Cardinals +1.5 ($1.59), Astros -1.5 ($2.45)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.95 and the Astros at $1.87.

The Cardinals are 1.5-run underdogs against the Astros, with odds of $1.59 available at TAB.

For the favourite Astros (-1.5) to cover the line, TAB offers odds of $2.45.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 61% of the time, while the 8.5-run over/under is expected to stay under 54% of the time.

Cardinals vs Astros: Best Bets

  • Head to Head: Houston at $1.87 with TAB
  • Line: Cardinals +1.5 at $1.59 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

Our Cardinals vs Astros best bets are based on complex simulations and wagering expertise to help you place better bets with your chosen online bookie.

Cardinals vs Astros: Prediction

Stats Insider provides full coverage of the St. Louis vs Houston game on Thursday, including data-driven predictions and free tips.

Our model updates frequently, so refresh this article for the latest betting analysis before the St. Louis vs Houston game.

As always, see Stats Insider's Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.

Cardinals vs Astros: Essential Details

The match-up between the Cardinals and Astros at Busch Stadium is scheduled to commence at 3:15am AEST on Thursday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our St. Louis vs Houston predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you choose to use our MLB predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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