Colts vs Bills Prediction and Preview - NFL Week 10, 2024
Last updated: Nov 10, 2024, 5:56PM | Published: Nov 3, 2024, 6:02PM
The Indianapolis Colts will take on the favoured Buffalo Bills in NFL Week 10 action at Lucas Oil Stadium on Monday, starting at 5:00am AEDT.
This article features Stats Insider's best betting tips for the Colts vs Bills game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the result of Monday's Indianapolis vs Buffalo NFL game 10,000 times.
Our proven predictive analytics model currently gives the Bills a 65% chance of defeating the Colts in Week 10 of the NFL season.
Colts vs Bills: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Lucas Oil Stadium are shown below:
- Head to Head: Colts $2.85, Bills $1.44
- Line: Colts +4.5 ($1.91), Bills -4.5 ($1.91)
- Total (Over/Under 47 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Colts at $2.85 and the Bills at $1.44.
The Colts are 4.5-point underdogs against the Bills, with odds of $1.91 available at Bet365.
For the favourite Bills (-4.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 47 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Colts (+4.5) are predicted to cover the line 54% of the time, while the 47-point over/under is expected to stay under 52% of the time.
Colts vs Bills: Best Bets
- Head to Head: Indianapolis at $2.85 with Bet365
- Line: Colts +4.5 at $1.91 with Bet365
- Total Points: Under 47 at $1.91 with Bet365
While the Bills have a higher chance of winning the game, betting on the Colts to win is our recommended option due to the edge identified when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges published on Stats Insider is one of the keys to achieving long-term profitability.
Colts vs Bills: Prediction
Stats Insider's predicted final score for Colts vs Bills at Lucas Oil Stadium in Week 10 is the Bills winning 25-21.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Indianapolis vs Buffalo game in Week 10, including data-driven predictions and live win probabilitiestips.
For in-depth analysis from US experts,, check out Dimers' detailed Colts vs Bills prediction.
Colts vs Bills: TD Scorer Tips
Who will score the first touchdown in Colts vs Bills? The latest data is in.
According to Stats Insider, Indianapolis' Jonathan Taylor is the most likely player to score the first TD in Colts vs Bills.
Taylor has a 15.0% chance of getting in for six first at Lucas Oil Stadium, while the Colts RB has a 58.4% chance of scoring an anytime touchdown.
Scroll down for the full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Colts First TD Tips
- Jonathan Taylor: 15.0% probability
- Josh Downs: 7.0% probability
- Alec Pierce: 5.0% probability
- Joe Flacco: 4.9% probability
- Adonai Mitchell: 4.0% probability
Bills First TD Tips
- Josh Allen: 12.5% probability
- James Cook: 10.1% probability
- Khalil Shakir: 7.8% probability
- Dalton Kincaid: 6.3% probability
- Mack Hollins: 5.6% probability
Anytime Touchdown Scorer Tips
Colts Anytime TD Tips
- Jonathan Taylor: 58.4% probability
- Josh Downs: 33.2% probability
- Joe Flacco: 24.2% probability
- Alec Pierce: 23.6% probability
- Adonai Mitchell: 19.8% probability
Bills Anytime TD Tips
- Josh Allen: 50.3% probability
- James Cook: 44.7% probability
- Khalil Shakir: 33.5% probability
- Dalton Kincaid: 29.4% probability
- Mack Hollins: 25.9% probability
Colts-Bills Projected Player Stats
Of the starting quarterbacks, the Colts' Joe Flacco is projected for 236 passing yards. The Bills' Josh Allen is expected to throw for 243 yards.
Colts Starting QB
- Joe Flacco: 236 projected passing yards
Bills Starting QB
- Josh Allen: 243 projected passing yards
Colts Rushing Yards
- Jonathan Taylor: 87 projected yards
- Trey Sermon: 11 projected yards
- Joe Flacco: 8 projected yards
Bills Rushing Yards
- James Cook: 70 projected yards
- Josh Allen: 36 projected yards
- Ray Davis: 22 projected yards
Colts Receiving Yards
- Josh Downs: 58 projected yards
- Alec Pierce: 37 projected yards
- Adonai Mitchell: 37 projected yards
- Jonathan Taylor: 17 projected yards
- Ashton Dulin: 15 projected yards
Bills Receiving Yards
- Khalil Shakir: 68 projected yards
- Dalton Kincaid: 51 projected yards
- Mack Hollins: 31 projected yards
- James Cook: 19 projected yards
- Ty Johnson: 16 projected yards
Remember, our model updates regularly, so bookmark this article for the latest betting analysis before the Indianapolis vs Buffalo match-up.
As always, see our Best Bets for betting tips on every NFL game, as well as predictions for a wide range of other sports.
Colts vs Bills: Week 10 Essential Details
The NFL Week 10 game between the Colts and Bills at Lucas Oil Stadium is scheduled to start at 5:00am AEDT on Monday.
- Teams: Indianapolis Colts vs Buffalo Bills
- Date: Monday 11 November 2024
- Time: 5:00am AEDT
- Venue: Lucas Oil Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Indianapolis vs Buffalo predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our NFL predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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