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Cubs vs Padres Prediction and MLB Tips - 5 April 2025

The Chicago Cubs will sqaure off with the San Diego Padres in MLB action at Wrigley Field on Saturday, starting at 5:20am AEDT.

The Cubs will have Shota Imanaga (1-0, 0.82 ERA) start, up against Randy Vásquez (0-0, 0.00 ERA) for the Padres.

This article features Stats Insider's prediction and tips for the Cubs vs Padres game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the outcome of Saturday's Cubs vs San Diego MLB match-up 10,000 times.

Our leading predictive analytics model gives the Cubs a 59% chance of winning against the Padres at Wrigley Field.

Cubs vs Padres: Odds

The current betting odds in Australia for Saturday's MLB game at Wrigley Field are shown below:

  • Head to Head: Cubs $1.60, Padres $2.43
  • Line: Cubs -1.5 ($2.43), Padres +1.5 ($1.56)
  • Total (Over/Under 6.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.60 and the Padres at $2.43.

The Cubs are 1.5-run favourites against the Padres, with odds of $2.43 available at TAB.

For the underdog Padres (+1.5) to cover the line, TAB offers odds of $1.56.

The over/under for total runs scored is set at 6.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Padres (+1.5) are predicted to cover the line 62% of the time, while the 6.5-run over/under is expected to go over 56% of the time.

Cubs vs Padres: Best Bets

  • Head to Head: San Diego at $2.43 with TAB
  • Line: Padres +1.5 at $1.56 with TAB
  • Total Runs: Over 6.5 at $1.91 with TAB

Stats Insider's Cubs vs Padres betting tips are based on detailed simulations and gambling expertise to give you the best possible advice 24/7/365.

While the Cubs have a higher chance of winning the game, betting on the Padres to win is our recommended option because of the 1.8% edge found when comparing our data-driven probabilities to the odds currently available.

Making use of the edges seen here at Stats Insider is one of the keys to achieving long-term profitability.

Cubs vs Padres: Prediction

Stats Insider provides full coverage of the Cubs vs San Diego game on Saturday, including data-driven predictions and free betting tips.

Remember, our model updates frequently, so refresh this article for the latest betting analysis before the Cubs vs San Diego game.

As always, see Stats Insider's Best Bets for the best tips for every MLB game, plus predictions for a wide range of other sports.

Cubs vs Padres: Essential Details

The match-up between the Cubs and Padres at Wrigley Field is scheduled to start at 5:20am AEDT on Saturday.

All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.

Conclusion

Our Cubs vs San Diego predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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