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Padres vs Guardians Prediction and MLB Tips - 2 April 2025

The San Diego Padres will take on the Cleveland Guardians in MLB action at PETCO Park on Wednesday, beginning at 12:40pm AEDT.

The Padres will send Michael King (0-0, 10.12 ERA) to the mound, up against Logan Allen (0-0, 0.00 ERA) for the Guardians.

This article features Stats Insider's prediction and tips for the Padres vs Guardians game, plus the latest betting odds in Australia.

Who Will Win?

Based on advanced computer power and data, Stats Insider has simulated the outcome of Wednesday's San Diego vs Cleveland MLB game 10,000 times.

Our independent predictive analytics model currently gives the Padres a 60% chance of winning against the Guardians at PETCO Park.

Padres vs Guardians: Odds

The current betting odds in Australia for Wednesday's MLB game at PETCO Park are listed below:

  • Head to Head: Padres $1.59, Guardians $2.45
  • Line: Padres -1.5 ($2.25), Guardians +1.5 ($1.67)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.59 and the Guardians at $2.45.

The Padres are listed as 1.5-run favourites against the Guardians, with odds of $2.25 available at TAB.

For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $1.67.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Guardians (+1.5) are predicted to cover the line 58% of the time, while the 7.5-run over/under is expected to stay under 52% of the time.

Padres vs Guardians: Betting Tips

  • Head to Head: Cleveland at $2.45 with TAB
  • Line: Guardians +1.5 at $1.67 with TAB
  • Total Runs: Under 7.5 at $1.91 with TAB

Stats Insider's Padres vs Guardians predictions are based on detailed simulations and wagering experience to bring you the best possible advice every time.

While the Padres have a higher chance of winning the game, betting on the Guardians to win is our recommended option because of the edge found when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges seen here at Stats Insider is one of the keys to being profitable in the long run.

Padres vs Guardians: Prediction

Stats Insider provides full betting coverage of the San Diego vs Cleveland game on Wednesday, including data-driven predictions and the best betting tips.

Remember, our model updates frequently, so keep checking this article for the latest betting analysis before the San Diego vs Cleveland game.

As always, see Stats Insider's Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.

Padres vs Guardians: Essential Details

The game between the Padres and Guardians at PETCO Park is scheduled to begin at 12:40pm AEDT on Wednesday.

All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.

Conclusion

Our San Diego vs Cleveland predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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