Panthers vs Cowboys Prediction and Tips - NRL Round 5, 2025
Mar 31, 2025, 12:21AM
The Panthers will face the Cowboys in NRL Round 5 action at Panthers Stadium on Friday, commencing at 6:00pm AEDT.
This article features Stats Insider's prediction and tips for the Panthers vs Cowboys game, plus the latest betting odds.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the result of Friday's Penrith vs North Queensland NRL match 10,000 times.
Our leading predictive analytics model currently gives the Panthers an 81% chance of winning against the Cowboys at Panthers Stadium.
Panthers vs Cowboys: Odds
The latest Bet365 betting odds for Friday's NRL clash at Panthers Stadium are shown below:
- Head to Head: Panthers $1.25, Cowboys $4.00
- Line: Panthers -11.5 ($1.91), Cowboys +11.5 ($1.91)
- Total (Over/Under 49.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Panthers at $1.25 and the Cowboys at $4.00.
The Panthers are listed as 11.5-point favourites against the Cowboys, with odds of $1.91 available at Bet365.
For the underdog Cowboys (+11.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 49.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Panthers (-11.5) are predicted to cover the line 54% of the time, while the 49.5-point over/under is expected to stay under 58% of the time.
Panthers vs Cowboys: Betting Tips
- Head to Head: Panthers at $1.25 with Bet365
- Line: Panthers -11.5 at $1.91 with Bet365
- Total Points: Under 49.5 at $1.91 with Bet365
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Panthers vs Cowboys: Prediction
Stats Insider's predicted final score for Panthers vs Cowboys at Panthers Stadium this Friday is the Panthers winning 29-16.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Panthers vs Cowboys match on Friday, including data-driven predictions and live win probabilitiestips.
Our model updates regularly, so refresh this article for the latest betting predictions before the Panthers vs Cowboys game.
As always, see our Best Bets for betting tips for every NRL match, plus predictions for a wide range of other sports.
Panthers vs Cowboys: Essential Details
The NRL Round 5 clash between the Panthers and Cowboys at Panthers Stadium is scheduled to begin at 6:00pm AEDT on Friday.
- Teams: Penrith Panthers vs North Queensland Cowboys
- Date: Friday 4 April 2025
- Kick-off: 6:00pm AEDT
- Location: Panthers Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Panthers vs Cowboys predictions are the result of 10,000 data-driven simulations of the match, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our rugby league tips are trustworthy and reliable, giving you the confidence to make informed decisions.
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