Panthers vs Cowboys Prediction and Tips - NRL Round 5, 2025
Mar 31, 2025, 4:40PM
The Panthers will sqaure off with the Cowboys in NRL Round 5 action at Panthers Stadium on Friday, with kick-off at 6:00pm AEDT.
This article features Stats Insider's prediction and tips for the Panthers vs Cowboys game, along with the latest betting odds and try scorer tips.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the result of Friday's Penrith vs North Queensland NRL match 10,000 times.
Our proven predictive analytics model gives the Panthers an 82% chance of defeating the Cowboys at Panthers Stadium.
Panthers vs Cowboys: Odds
The current Bet365 betting odds for Friday's NRL clash at Panthers Stadium are listed here:
- Head to Head: Panthers $1.22, Cowboys $4.25
- Line: Panthers -12.5 ($1.91), Cowboys +12.5 ($1.91)
- Total (Over/Under 50.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Panthers at $1.22 and the Cowboys at $4.25.
The Panthers are 12.5-point favourites against the Cowboys, with odds of $1.91 available at Bet365.
For the underdog Cowboys (+12.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 50.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Panthers (-12.5) are predicted to cover the line 55% of the time, while the 50.5-point over/under is expected to stay under 62% of the time.
Panthers vs Cowboys: Betting Tips
- Head to Head: Panthers at $1.22 with Bet365
- Line: Panthers -12.5 at $1.91 with Bet365
- Total Points: Under 50.5 at $1.91 with Bet365
If you see a 🔥, you know it's one of Stats Insider's best bets of the day across all sports.
Our Panthers vs Cowboys predictions are based on world-class modelling and wagering experience to bring you the best possible advice every time.
Panthers vs Cowboys: Prediction
Stats Insider's predicted final score for Panthers vs Cowboys at Panthers Stadium on Friday is the Panthers winning 29-15.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full betting coverage of the Panthers vs Cowboys match on Friday, including data-driven predictions and top betting tips.
18+. Odds correct at time of publishing and subject to change.Panthers vs Cowboys: Try Scorers
Are you looking for Panthers vs Cowboys try scorers? The latest data is in.
According to Stats Insider, the Panthers' Casey McLean is the most likely player to score the first try in Penrith vs North Queensland.
McLean has a 8.6% chance of scoring the first try at Panthers Stadium, while the Panthers star has a 53.4% chance of scoring a try at any time during the match.
Scroll down for our complete list of first try scorer and anytime try scorer probabilities.
First Try Scorer Tips
Penrith Panthers
- Casey McLean: 8.6% probability
- Paul Alamoti: 8.5% probability
- Izack Tago: 6.8% probability
- Thomas Jenkins: 5.8% probability
- Nathan Cleary: 5.5% probability
North Queensland Cowboys
- Murray Taulagi: 5.4% probability
- Robert Derby: 4.5% probability
- Jaxon Purdue: 4.0% probability
- Scott Drinkwater: 3.9% probability
- Tom Dearden: 3.0% probability
Anytime Try Scorer Tips
Penrith Panthers
- Casey McLean: 53.4% probability
- Paul Alamoti: 52.9% probability
- Izack Tago: 43.2% probability
- Thomas Jenkins: 39.3% probability
- Nathan Cleary: 37.4% probability
North Queensland Cowboys
- Murray Taulagi: 35.6% probability
- Robert Derby: 32.2% probability
- Scott Drinkwater: 28.6% probability
- Jaxon Purdue: 27.4% probability
- Tom Dearden: 24.0% probability
Remember, our model updates regularly, so keep checking this article for the latest betting analysis before the Panthers vs Cowboys match.
As always, see Stats Insider's Best Bets for betting tips on every NRL match, plus predictions for a wide range of other sports.
Panthers vs Cowboys: Essential Details
The NRL Round 5 clash between the Panthers and Cowboys at Panthers Stadium is scheduled to start at 6:00pm AEDT on Friday.
- Teams: Penrith Panthers vs North Queensland Cowboys
- Date: Friday 4 April 2025
- Kick-off: 6:00pm AEDT
- Location: Panthers Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Panthers vs Cowboys predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our rugby league tips are accurate and reliable, giving you the confidence to make informed decisions.
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