Pirates vs Guardians Prediction and MLB Tips - 21 April 2025
Apr 20, 2025, 1:29AM
The Pittsburgh Pirates will sqaure off with the Cleveland Guardians in MLB action at PNC Park on Monday, beginning at 3:35am AEST.
The Pirates will have Mitch Keller (1-2, 4.30 ERA) start, while the Guardians will counter with Logan Allen (1-1, 2.30 ERA).
This article features Stats Insider's prediction and tips for the Pirates vs Guardians game, along with the latest betting odds in Australia.
Who Will Win?
Based on advanced computer power and data, Stats Insider has simulated the outcome of Monday's Pittsburgh vs Cleveland MLB game 10,000 times.
Our independent predictive analytics model gives the Pirates a 51% chance of winning against the Guardians at PNC Park.
Pirates vs Guardians: Odds
The latest betting odds in Australia for Monday's MLB game at PNC Park are shown here:
- Head to Head: Pirates $1.87, Guardians $1.95
- Line: Pirates +1.5 ($1.53), Guardians -1.5 ($2.60)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.87 and the Guardians at $1.95.
The Pirates are listed as 1.5-run underdogs against the Guardians, with odds of $1.53 available at TAB.
For the favourite Guardians (-1.5) to cover the line, TAB offers odds of $2.60.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Pirates (+1.5) are predicted to cover the line 64% of the time, while the 8-run over/under is expected to stay under 54% of the time.
Pirates vs Guardians: Best Bets
- Head to Head: Cleveland at $1.95 with TAB
- Line: Pirates +1.5 at $1.53 with TAB
- Total Runs: Under 8 at $1.91 with TAB
These Pirates vs Guardians predictions are based on market-leading modelling and betting expertise to bring you the best possible advice 24/7/365.
While the Pirates have a higher chance of winning the game, betting on the Guardians to win is our preferred option due to the edge found when comparing our data-driven probabilities to the odds currently available.
Making use of the edges published on Stats Insider is crucial to achieving long-term success as a sports bettor.
Pirates vs Guardians: Prediction
Stats Insider provides full coverage of the Pittsburgh vs Cleveland game on Monday, including data-driven predictions and the best betting tips.
Remember, our model updates frequently, so bookmark this page for the latest betting tips before the Pittsburgh vs Cleveland match-up.
As always, see our Best Bets to get betting tips on every MLB game, plus predictions for a wide range of other sports.
Pirates vs Guardians: Essential Details
The match-up between the Pirates and Guardians at PNC Park is scheduled to start at 3:35am AEST on Monday.
- Teams: Pittsburgh Pirates vs Cleveland Guardians
- Date: Monday 21 April 2025
- Time: 3:35am AEST
- Venue: PNC Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Pittsburgh vs Cleveland predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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