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Red Sox vs White Sox Prediction and MLB Tips - 21 April 2025

The Boston Red Sox will sqaure off with the Chicago White Sox in MLB action at Fenway Park on Monday, starting at 3:35am AEST.

Tanner Houck (0-2, 9.16 ERA) will start on the mound for the Red Sox, while the White Sox will counter with Sean Burke (1-3, 7.56 ERA).

This article features Stats Insider's prediction and tips for the Red Sox vs White Sox game, along with the latest betting odds in Australia.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the result of Monday's Boston vs White Sox MLB match-up 10,000 times.

Our proven predictive analytics model currently gives the Red Sox a 69% chance of beating the White Sox at Fenway Park.

Red Sox vs White Sox: Odds

The latest betting odds in Australia for Monday's MLB game at Fenway Park are listed below:

  • Head to Head: Red Sox $1.36, White Sox $3.30
  • Line: Red Sox -1.5 ($1.77), White Sox +1.5 ($2.10)
  • Total (Over/Under 9 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Red Sox at $1.36 and the White Sox at $3.30.

The Red Sox are 1.5-run favourites against the White Sox, with odds of $1.77 available at TAB.

For the underdog White Sox (+1.5) to cover the line, TAB offers odds of $2.10.

The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Red Sox (-1.5) are predicted to cover the line 51% of the time, while the 9-run over/under is expected to stay under 56% of the time.

Red Sox vs White Sox: Best Bets

  • Head to Head: White Sox at $3.30 with TAB
  • Line: White Sox +1.5 at $2.10 with TAB
  • Total Runs: Under 9 at $1.91 with TAB

These Red Sox vs White Sox betting tips are based on market-leading simulations and betting expertise to help you place smarter bets with your chosen online bookie.

And while the Red Sox have a higher chance of winning the game, betting on the White Sox to win is our preferred option due to the 1.7% edge found when comparing our data-led probabilities to the odds currently on offer.

Making use of the edges seen here at Stats Insider is one of the keys to achieving long-term profitability.

Although the Red Sox are more likely to cover the line, our best bet of White Sox +1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the top odds available.

Red Sox vs White Sox: Prediction

Stats Insider provides full betting coverage of the Boston vs White Sox game on Monday, including data-driven predictions and live scorestips.

Our model updates regularly, so refresh this article for the latest betting analysis before the Boston vs White Sox match-up.

As always, see Stats Insider's Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.

Red Sox vs White Sox: Essential Details

The match-up between the Red Sox and White Sox at Fenway Park is scheduled to start at 3:35am AEST on Monday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Boston vs White Sox predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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