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Reds vs Mariners Prediction and MLB Tips - 16 April 2025

The Cincinnati Reds will sqaure off with the Seattle Mariners in MLB action at Great American Ball Park on Wednesday, commencing at 8:40am AEST.

The Reds will have Nick Lodolo (2-1, 0.96 ERA) start, pitting him against Luis Castillo (1-1, 2.12 ERA) for the Mariners.

This article features Stats Insider's prediction and tips for the Reds vs Mariners game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising trusted machine learning and data, Stats Insider has simulated the result of Wednesday's Cincinnati vs Seattle MLB game 10,000 times.

Our leading predictive analytics model gives the Reds a 53% chance of defeating the Mariners at Great American Ball Park.

Reds vs Mariners: Odds

The latest betting odds in Australia for Wednesday's MLB game at Great American Ball Park are shown here:

  • Head to Head: Reds $1.95, Mariners $1.87
  • Line: Reds +1.5 ($1.61), Mariners -1.5 ($2.40)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Reds at $1.95 and the Mariners at $1.87.

The Reds are 1.5-run underdogs against the Mariners, with odds of $1.61 available at TAB.

For the favourite Mariners (-1.5) to cover the line, TAB offers odds of $2.40.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Reds (+1.5) are predicted to cover the line 64% of the time, while the 8.5-run over/under is expected to stay under 52% of the time.

Reds vs Mariners: Betting Tips

  • Head to Head: Cincinnati at $1.95 with TAB
  • Line: Reds +1.5 at $1.61 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

If you see a 🔥, that means it's one of our best tips for today across any sport.

Our Reds vs Mariners predictions are based on complex modelling and gambling experience to help you place smarter bets with your chosen online bookie.

Reds vs Mariners: Prediction

Stats Insider provides full betting coverage of the Cincinnati vs Seattle game on Wednesday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates regularly, so bookmark this page for the latest betting tips before the Cincinnati vs Seattle match-up.

As always, see our Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.

Reds vs Mariners: Essential Details

The game between the Reds and Mariners at Great American Ball Park is scheduled to begin at 8:40am AEST on Wednesday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cincinnati vs Seattle predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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