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Tigers vs Padres Prediction and MLB Tips - 22 April 2025

The Detroit Tigers will face the San Diego Padres in MLB action at Comerica Park on Tuesday, beginning at 8:40am AEST.

Keider Montero (0-1, 9.00 ERA) will get the ball for the Tigers, while the Padres will counter with Randy Vásquez (1-1, 1.74 ERA).

This article features Stats Insider's prediction and tips for the Tigers vs Padres game, along with the latest betting odds in Australia.

Who Will Win?

Based on advanced computer power and data, Stats Insider has simulated the result of Tuesday's Detroit vs San Diego MLB match-up 10,000 times.

Our proven predictive analytics model gives the Tigers a 53% chance of defeating the Padres at Comerica Park.

Tigers vs Padres: Odds

The latest betting odds in Australia for Tuesday's MLB game at Comerica Park are listed below:

  • Head to Head: Tigers $1.76, Padres $2.11
  • Line: Tigers -1.5 ($2.58), Padres +1.5 ($1.52)
  • Total (Over/Under 8.2 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Tigers at $1.76 and the Padres at $2.11.

The Tigers are listed as 1.5-run favourites against the Padres, with odds of $2.58 available at TAB.

For the underdog Padres (+1.5) to cover the line, TAB offers odds of $1.52.

The over/under for total runs scored is set at 8.2 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Padres (+1.5) are predicted to cover the line 64% of the time, while the 8.2-run over/under is expected to go over 51% of the time.

Tigers vs Padres: Best Bets

  • Head to Head: San Diego at $2.11 with TAB
  • Line: Padres +1.5 at $1.52 with TAB
  • Total Runs: Over 8.2 at $1.91 with TAB

Our Tigers vs Padres best bets are based on complex simulations and wagering intelligence to help you place more informed bets with your chosen online bookie.

While the Tigers have a higher chance of winning the game, betting on the Padres to win is our preferred option due to the 1.2% edge found when comparing our data-driven probabilities to the odds currently on offer.

Taking advantage of the edges seen here at Stats Insider is one of the keys to being a profitable sports bettor in the long run.

Tigers vs Padres: Prediction

Stats Insider provides full coverage of the Detroit vs San Diego game on Tuesday, including data-driven predictions and live scorestips.

Remember, our model updates regularly, so keep checking this article for the latest betting analysis before the Detroit vs San Diego match-up.

As always, see our Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.

Tigers vs Padres: Essential Details

The game between the Tigers and Padres at Comerica Park is scheduled to start at 8:40am AEST on Tuesday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Detroit vs San Diego predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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